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Memet Emin
03-05-08, 19:58
Uyghur Geni Toghursida Ilmi Maqala

Amirka Insanlar Geni Ilmi Jemiyiti Jornili (The American Journal of Human Genetics) ning 2008-yili 3-ayning 20-kunidiki sanida Junggo Penler Akidimiyesi, Shangxay Fudan University, Junggo Dowletlik Insanlar Geni Merkizi qatarliq organalardiki pen texnika tetqiqat xadimliri teripidin ilan qilghan Uyghurlarning Geni Toghursidiki bir parche maqale ilan qilinghan bolup, bu maqalida Uyghurlar genining 60% Yawropa irqige (aq tenlikler irqige), 40% Asiya irqige (yeni siriq tenlikler irqige) tewe ikenligi oturgha qoyulghan. Bu maqalida diyilishche Uyghurlar genidiki bu arilashma texminen 2520 yil (2140 yildin 2920 yil) ilgiri bashlanghan iken.

Tepsilatigha qizziqidighanlar towendiki ulanmidin korse bolidu.

Copyright 2008 The American Society of Human Genetics. All rights reserved.
The American Journal of Human Genetics, Volume 82, Issue 4, 883-894, 20 March 2008

Analysis of Genomic Admixture in Uyghur and Its Implication in Mapping Strategy

Shuhua Xu1, 2, Wei Huang3, Ji Qian2 and Li Jin1, 2, ,
1 Chinese Academy of Sciences and Max Planck Society (CAS-MPG) Partner Institute for Computational Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China
2 Ministry of Education (MOE) Key Laboratory of Contemporary Anthropology and Center for Evolutionary Biology, School of Life Sciences and Institutes of Biomedical Sciences, Fudan University, Shanghai 200433, China
3 Chinese National Human Genome Center at Shanghai, Shanghai 201203, China

The Uyghur (UIG) population, settled in Xinjiang, China, is a population presenting a typical admixture of Eastern and Western anthropometric traits. We dissected its genomic structure at population level, individual level, and chromosome level by using 20,177 SNPs spanning nearly the entire chromosome 21. Our results showed that UIG was formed by two-way admixture, with 60% European ancestry and 40% East Asian ancestry. Overall linkage disequilibrium (LD) in UIG was similar to that in its parental populations represented in East Asia and Europe with regard to common alleles, and UIG manifested elevation of LD only within 500 kb and at a level of 0.1 < r2 < 0.8 when ancestry-informative markers (AIMs) were used. The size of chromosomal segments that were derived from East Asian and European ancestries averaged 2.4 cM and 4.1 cM, respectively. Both the magnitude of LD and fragmentary ancestral chromosome segments indicated a long history of Uyghur. Under the assumption of a hybrid isolation (HI) model, we estimated that the admixture event of UIG occurred about 126 [107 146] generations ago, or 2520 [2140 2920] years ago assuming 20 years per generation. In spite of the long history and short LD of Uyghur compared with recent admixture populations such as the African-American population, we suggest that mapping by admixture LD (MALD) is still applicable in the Uyghur population but 10-fold AIMs are necessary for a whole-genome scan.

http://www.ajhg.org/AJHG/fulltext/S0002-9297%2808%2900166-3

"Gen"ni
05-05-08, 13:34
Uyghur Geni Toghursida Ilmi Maqala

Amirka Insanlar Geni Ilmi Jemiyiti Jornili (The American Journal of Human Genetics) ning 2008-yili 3-ayning 20-kunidiki sanida Junggo Penler Akidimiyesi, Shangxay Fudan University, Junggo Dowletlik Insanlar Geni Merkizi qatarliq organalardiki pen texnika tetqiqat xadimliri teripidin ilan qilghan Uyghurlarning Geni Toghursidiki bir parche maqale ilan qilinghan bolup, bu maqalida Uyghurlar genining 60% Yawropa irqige (aq tenlikler irqige), 40% Asiya irqige (yeni siriq tenlikler irqige) tewe ikenligi oturgha qoyulghan. Bu maqalida diyilishche Uyghurlar genidiki bu arilashma texminen 2520 yil (2140 yildin 2920 yil) ilgiri bashlanghan iken.

Tepsilatigha qizziqidighanlar towendiki ulanmidin korse bolidu.

Copyright 2008 The American Society of Human Genetics. All rights reserved.
The American Journal of Human Genetics, Volume 82, Issue 4, 883-894, 20 March 2008

Analysis of Genomic Admixture in Uyghur and Its Implication in Mapping Strategy

Shuhua Xu1, 2, Wei Huang3, Ji Qian2 and Li Jin1, 2, ,
1 Chinese Academy of Sciences and Max Planck Society (CAS-MPG) Partner Institute for Computational Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China
2 Ministry of Education (MOE) Key Laboratory of Contemporary Anthropology and Center for Evolutionary Biology, School of Life Sciences and Institutes of Biomedical Sciences, Fudan University, Shanghai 200433, China
3 Chinese National Human Genome Center at Shanghai, Shanghai 201203, China

The Uyghur (UIG) population, settled in Xinjiang, China, is a population presenting a typical admixture of Eastern and Western anthropometric traits. We dissected its genomic structure at population level, individual level, and chromosome level by using 20,177 SNPs spanning nearly the entire chromosome 21. Our results showed that UIG was formed by two-way admixture, with 60% European ancestry and 40% East Asian ancestry. Overall linkage disequilibrium (LD) in UIG was similar to that in its parental populations represented in East Asia and Europe with regard to common alleles, and UIG manifested elevation of LD only within 500 kb and at a level of 0.1 < r2 < 0.8 when ancestry-informative markers (AIMs) were used. The size of chromosomal segments that were derived from East Asian and European ancestries averaged 2.4 cM and 4.1 cM, respectively. Both the magnitude of LD and fragmentary ancestral chromosome segments indicated a long history of Uyghur. Under the assumption of a hybrid isolation (HI) model, we estimated that the admixture event of UIG occurred about 126 [107 146] generations ago, or 2520 [2140 2920] years ago assuming 20 years per generation. In spite of the long history and short LD of Uyghur compared with recent admixture populations such as the African-American population, we suggest that mapping by admixture LD (MALD) is still applicable in the Uyghur population but 10-fold AIMs are necessary for a whole-genome scan.

http://www.ajhg.org/AJHG/fulltext/S0002-9297%2808%2900166-3

Hormetlik Memet Emin. yollanmingiznidiki, siz terjime qilghan jumlilerni oqupla, Uyghurlarning Genidiki 60% Yawrupaliqqa tewe Gen Musteqilliq uchun kuresh qilidighan, 40% asiyaliq Seriq tenliklerge tewe bolghan Gen, xainliq qilidighan Gen, yeni xitay arlash, xain Gen bolsa kerek,dep oylap qaldim. Men Gen tetqiqati ustide kop bir nerse bilmeymen. biraq daim oylaydighinim, Uyghur Inqilawidiki xainliq, kopunche hallarda arlashma qanliqlardin kelgen iken.........

Unregistered
05-05-08, 17:42
Bilmisingiz kalaymikan het yezip olturnang. Hainlar her kandak millette bar. Bolupmu hitaydek bir hain terbileydigan dolette.

Hormetlik Memet Emin. yollanmingiznidiki, siz terjime qilghan jumlilerni oqupla, Uyghurlarning Genidiki 60% Yawrupaliqqa tewe Gen Musteqilliq uchun kuresh qilidighan, 40% asiyaliq Seriq tenliklerge tewe bolghan Gen, xainliq qilidighan Gen, yeni xitay arlash, xain Gen bolsa kerek,dep oylap qaldim. Men Gen tetqiqati ustide kop bir nerse bilmeymen. biraq daim oylaydighinim, Uyghur Inqilawidiki xainliq, kopunche hallarda arlashma qanliqlardin kelgen iken.........

Unregistered
05-05-08, 19:22
I guess DNA does not lie. This sounds about right based on the physical appearance modern Uyghurs and some of the Taklamakan mummies. Asian genes perhaps represent Mongoloid ancestors from the steppes while the Caucasian genes represent the original Tarim people who were described by Zhang Qian as having green eyes.

Unregistered
06-05-08, 03:45
Hormetlik Memet Emin. yollanmingiznidiki, siz terjime qilghan jumlilerni oqupla, Uyghurlarning Genidiki 60% Yawrupaliqqa tewe Gen Musteqilliq uchun kuresh qilidighan, 40% asiyaliq Seriq tenliklerge tewe bolghan Gen, xainliq qilidighan Gen, yeni xitay arlash, xain Gen bolsa kerek,dep oylap qaldim. Men Gen tetqiqati ustide kop bir nerse bilmeymen. biraq daim oylaydighinim, Uyghur Inqilawidiki xainliq, kopunche hallarda arlashma qanliqlardin kelgen iken.........
Yuquridiki pikirni yazghan Uyghurgha:
Essalamu eleykum!
Gen-Uyghurlar özi talliwalidighan,bazardin tallap alidighan alma emes!Buni tallash hoquqi sizge berilmigen.Allah sizge ejdatliringiz wastisi bilen ötküzüp qoyghan nerse.
Sizningche bolghanda Yawropaliq bolsa shereplik bolidighan, aq tenlik bolsa shereplik bolidighan ishmiken? Wu chirayliq ependimi hörülqa xanim!
Gep qilishtin buurn sel oylinip andin qelemni qolgha eling.
Uyghurlar asasen musulman. Eger siz gheyri musulman bolmisingiz biliweling:
Muhemmed peyghembirimiz, musulman bolghanlarning qedr-qimmiti, uning Erep bolushi, Erep bolmasliqi, Aq tenlik bolushi, seriq tenlik we yaki qara tenlik bolushi bilen alaqisi bolmaydu. Kim Allahtin eng qorqsa, Allah digenni qilsa, qanche teqwa bolsa Allah aldida shunche izzetlik, qimmetlik bolidu.
Aq tenlik, Seriq tenlik, qara tenlik dep ayrish-shermende yawropa irqchiliri otturigha qoyghan telimat bolup tamamen batildur we Allahqa isyan qilish, Muhemmed peyghemberni we sünnetni inkar qilish asasida otturigha chiqirilghan. Burun bilmigen bolsingiz biliweling.Yawropaliqlar asasen sherepsiz,asasen xain. Asiyaliqlar eksiche.Bunimu biliweling.
Ülpetdishing qargha bolsa yiyishing poq,digen gep bar.Siz mektepte yaki öyingizde oqughan kitapni Yawropaliq nomussisz xain yaki xain,Allah düshmini yehudi yazghan bolsa sizning kallingiznimu qochuwetti digen gep. Shunga bundin keyin Quran we hedis üginip kallingizdiki kirlerni yuyiwetip pakiz tepekkur qiling.Allah sizni hidayet qilsun.
Alahni tonumighan,Muhemmed eleyhissalamning peyghemberlikige iman keltürmigen köngli qara,xain yawropaliqlarni chong bilmeng.Mushunchilk ders berey bügünche.

Unregistered
06-05-08, 13:54
Dimek Uyghurlarning Geni Ahtenlikken De He? Halimiz Siganlardin Beter Genimiz Ahtenlikken He?genimiz Ahtenlik Bolsa Nime Bolidiken Emdi,uyghur Helikining Turmuxida Nime Uzguruxbulidiken?xunqe Qong Yerxarida Uyghur Helkining Dessep Turghudek Bir Yeriyoh Genimiz Ahtenlikken.genimiz Ahtenlikken Ata Bowimiz Dunyani Soraptiken Dep Uzimizni Uzimiz Hox Kilip Olturiwereyli!

Unregistered
14-05-08, 19:22
uyghurlarning genining %60 ak tenliklerningkige %40 i asyaliklarningkige ohshishi bir ilmi hekiket bolsimu buni bu shekilde siniflandurush bizni kemsitishtishtin bashka nerse emes. Bu hekiketni yavrupaliklarning genining %60 i asyaliklarning genining %40 i Uyghurlargha ohshash iken diyishkimu bolidu. Hazirki bizning siyasi ornimiz "mustemlike" bolghachka ilmi hekiketlerningmu ipadilinishi shuninggha asasen bolivatidu. Elbette dunyadiki putun insanlarning ohshash terepliri ve oshshimaydighan terepliri bar. Buninggha karighandimu genlardiki ohshashlik yaki ohshimasliklarning korulishi mukerer. Gen tekikikatshiliridin shundak bir soalni sorughum bar. Afrikidiki kara tenlikler bilen Uyghurlarning yaki hittaylarning genida
ohshashlik yokmu? miningche elbette bar diyeleymen. Chunki Ularmu, bizmu insan!
Biz oz aldimizgha ayrim irik. Akmu emes sirikmu emes. Ballirimizning arkisi kok tughulidighan
kok bori evladi digen rivayetke ishinidighan kok borilerning evladi. Tenngri bizni shundak yaratkan. shundak kalimiz ve shundak kilishimiz kirek.

Nekuto
14-05-08, 20:20
I understood what the autor tried mention at this posting. He /she wanted to mention that Uyghurs are much closer to Eurpean than Chines, as geneticly .This effort seing as proeuropian apperantley, actually it is truely indication of antichinese feeling and antichinese stance.

Today, there is noting wrong if someone became an proeuropian. becouse they were or are not occupied our country; on contrary they sometimes helping us and tried ristricting the chinese violation of human rights.

Here is the measure of good or bad nation on the world for Uyghurs: What or how is the nation's attitude to Chinese policy.

As far as I understanding Islam does not allow to raciesim , but Islam does not accused as raciesim that the idea leading to fighting for against the occupation.



QUOTE="Gen"ni;36358]Hormetlik Memet Emin. yollanmingiznidiki, siz terjime qilghan jumlilerni oqupla, Uyghurlarning Genidiki 60% Yawrupaliqqa tewe Gen Musteqilliq uchun kuresh qilidighan, 40% asiyaliq Seriq tenliklerge tewe bolghan Gen, xainliq qilidighan Gen, yeni xitay arlash, xain Gen bolsa kerek,dep oylap qaldim. Men Gen tetqiqati ustide kop bir nerse bilmeymen. biraq daim oylaydighinim, Uyghur Inqilawidiki xainliq, kopunche hallarda arlashma qanliqlardin kelgen iken.........[/QUOTE]

Diqqetqiling!
15-05-08, 14:44
Yuquridiki pikirni yazghan Uyghurgha:
Essalamu eleykum!
Gen-Uyghurlar özi talliwalidighan,bazardin tallap alidighan alma emes!Buni tallash hoquqi sizge berilmigen.Allah sizge ejdatliringiz wastisi bilen ötküzüp qoyghan nerse.
Sizningche bolghanda Yawropaliq bolsa shereplik bolidighan, aq tenlik bolsa shereplik bolidighan ishmiken? Wu chirayliq ependimi hörülqa xanim!
Gep qilishtin buurn sel oylinip andin qelemni qolgha eling.
Uyghurlar asasen musulman. Eger siz gheyri musulman bolmisingiz biliweling:
Muhemmed peyghembirimiz, musulman bolghanlarning qedr-qimmiti, uning Erep bolushi, Erep bolmasliqi, Aq tenlik bolushi, seriq tenlik we yaki qara tenlik bolushi bilen alaqisi bolmaydu. Kim Allahtin eng qorqsa, Allah digenni qilsa, qanche teqwa bolsa Allah aldida shunche izzetlik, qimmetlik bolidu.
Aq tenlik, Seriq tenlik, qara tenlik dep ayrish-shermende yawropa irqchiliri otturigha qoyghan telimat bolup tamamen batildur we Allahqa isyan qilish, Muhemmed peyghemberni we sünnetni inkar qilish asasida otturigha chiqirilghan. Burun bilmigen bolsingiz biliweling.Yawropaliqlar asasen sherepsiz,asasen xain. Asiyaliqlar eksiche.Bunimu biliweling.
Ülpetdishing qargha bolsa yiyishing poq,digen gep bar.Siz mektepte yaki öyingizde oqughan kitapni Yawropaliq nomussisz xain yaki xain,Allah düshmini yehudi yazghan bolsa sizning kallingiznimu qochuwetti digen gep. Shunga bundin keyin Quran we hedis üginip kallingizdiki kirlerni yuyiwetip pakiz tepekkur qiling.Allah sizni hidayet qilsun.
Alahni tonumighan,Muhemmed eleyhissalamning peyghemberlikige iman keltürmigen köngli qara,xain yawropaliqlarni chong bilmeng.Mushunchilk ders berey bügünche.
*******
tazimu bir "Siyasi kengesh"ke Molla qiliwalsa, bolghidek birikensiz. Yawrupaliq sizge neme yamanliq qilghan? Asiyaliqni mahtap qapsizghu! toghra, bizmu Asiyaliq. biraq putun Asiyaliqtin Uyghurgha ziyan keliwatidu. hewiringiz yoqmu ya? bizning Wetimiz "Asiyaning kindikide" dep pehirlinimiz. biraq bizge asiyaliqtin wapa kelmey, bala keliwatidu. unchiwala memedanliq qilip, addi bir hetimge Allahning, Peyghemberning Muqeddes kalamini delil kelturmisingizmu bolidu. ozingizning koz qarishingz bolsa, mertlerche otturgha qoysingiz, halayiq anglaydu. emma Allahning, peyghemberning kalamini desmi qilip, bashqilarni "Kapir"liq bilen qorqitip, soz yoghlatmang. nomus qiling. sizning Molla ikenligingizni bildim. biraq, bu yerdiki parang, siz eytiwatqandek" Kapir, Musulman"liq ustide emes. tazimu ahmaq biriken bu. Yawrupaliq Hain bolughan bolsa, siz bilen bizdek hane weyran kishilerni setip hejligen bolatti. bir Uyghurni Amerkiliqqa 5000 Dollerge setip hejligenler, yawrupaliq emes, siz mahtawatqan,asiyaliq- Pakistanliq. hitaygha tutup berip, qenini ichiwatqanlar, YAwrupaliq emes, qazaq, qirghiz, ozbek, hindi- hemmisi asiyaliq. deydighan yene gepliringiz bolsa, "Siyasi kengesh"ning Mollisidek, Quranggha esilip, helqni qaymuqturmay,oz pikringizni qoyup beqing. wetende sizdek Mollidin minglarche barki, hitay Amerikini, yawrupaliqni tillisa, sizdek Molla, hazir mushu yerde sozligingizdek, wetendimu Quran, hedis bilen delil kelturup tillaydu. perqi bolsun wetendiki Siyasi kengeshning mollisi bilen, erkin dunyadiki mollining!

Unregistered
15-05-08, 23:34
Qizil kommunist molla iken. Allahning namini setip putun iriq, helqni qoshup tillaptu. Yawrapaliqlarning ichidimu esil ademlerning barlighini , yahudilerning ichidimu hudagha seghinidighan ademlerning barlighini bilmey qaldingmu!! . Gen toghrisidiki sozung toghridek tursimu ahiridiki esebiyliking sening chala molla ikenligingni ispatlaptu.


Yuquridiki pikirni yazghan Uyghurgha:
Essalamu eleykum!
Gen-Uyghurlar özi talliwalidighan,bazardin tallap alidighan alma emes!Buni tallash hoquqi sizge berilmigen.Allah sizge ejdatliringiz wastisi bilen ötküzüp qoyghan nerse.
Sizningche bolghanda Yawropaliq bolsa shereplik bolidighan, aq tenlik bolsa shereplik bolidighan ishmiken? Wu chirayliq ependimi hörülqa xanim!
Gep qilishtin buurn sel oylinip andin qelemni qolgha eling.
Uyghurlar asasen musulman. Eger siz gheyri musulman bolmisingiz biliweling:
Muhemmed peyghembirimiz, musulman bolghanlarning qedr-qimmiti, uning Erep bolushi, Erep bolmasliqi, Aq tenlik bolushi, seriq tenlik we yaki qara tenlik bolushi bilen alaqisi bolmaydu. Kim Allahtin eng qorqsa, Allah digenni qilsa, qanche teqwa bolsa Allah aldida shunche izzetlik, qimmetlik bolidu.
Aq tenlik, Seriq tenlik, qara tenlik dep ayrish-shermende yawropa irqchiliri otturigha qoyghan telimat bolup tamamen batildur we Allahqa isyan qilish, Muhemmed peyghemberni we sünnetni inkar qilish asasida otturigha chiqirilghan. Burun bilmigen bolsingiz biliweling.Yawropaliqlar asasen sherepsiz,asasen xain. Asiyaliqlar eksiche.Bunimu biliweling.
Ülpetdishing qargha bolsa yiyishing poq,digen gep bar.Siz mektepte yaki öyingizde oqughan kitapni Yawropaliq nomussisz xain yaki xain,Allah düshmini yehudi yazghan bolsa sizning kallingiznimu qochuwetti digen gep. Shunga bundin keyin Quran we hedis üginip kallingizdiki kirlerni yuyiwetip pakiz tepekkur qiling.Allah sizni hidayet qilsun.
Alahni tonumighan,Muhemmed eleyhissalamning peyghemberlikige iman keltürmigen köngli qara,xain yawropaliqlarni chong bilmeng.Mushunchilk ders berey bügünche.